Panax Ginseng Induces Toxic Hepatitis and Acute Kidney Injury

نویسندگان

  • Jeong Ho Lee
  • Jung Hwan Yoon
  • Sung Sun Kim
  • Seong Kwon Ma
  • Soo Wan Kim
  • Eun Hui Bae
چکیده

https://doi.org/10.4068/cmj.2017.53.2.168 C Chonnam Medical Journal, 2017 Chonnam Med J 2017;53:168-169 Corresponding Author: Eun Hui Bae Department of Internal Medicine, Chonnam National University Medical School, 42 Jebong-ro, Dong-gu, Gwangju 61469, Korea Tel: +82-62-220-6503, Fax: +82-62-225-8578, E-mail: [email protected] Article History: Received February 9, 2017 Revised March 5, 2017 Accepted March 7, 2017 FIG. 1. Microscopic image shows interstitial mononuclear cell infiltrate with edema (hematoxyline and eosin stain, magnification 200×). Panax Ginseng Induces Toxic Hepatitis and Acute Kidney Injury Jeong Ho Lee, Jung Hwan Yoon, Sung Sun Kim, Seong Kwon Ma, Soo Wan Kim, and Eun Hui Bae* Departments of Internal Medicine, Pathology, Chonnam National University Medical School, Gwangju, Korea

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Ginseng extract and ginsenoside Rb1 attenuate carbon tetrachloride-induced liver fibrosis in rats

BACKGROUND Ginsenosides, the major bioactive compounds in ginseng root, have been found to have antioxidant, immunomodulatory and anti-inflammatory activities. This study investigated the effects of ginsenosides on carbon tetrachloride (CCl4)-induced hepatitis and liver fibrosis in rats. METHODS Male Sprague-Dawley rats were randomly divided into four groups: control, CCl4, CCl4 + 0.5 g/kg Pa...

متن کامل

Protective effect of wild ginseng cambial meristematic cells on d-galactosamine-induced hepatotoxicity in rats

BACKGROUND Panax ginseng has a wide range of biological activities including anti-inflammatory, antioxidant, and immunomodulatory functions. Wild ginseng cambial meristematic cells (CMCs) were obtained from P. ginseng cambium. This study examined the protective mechanism of wild ginseng CMCs against d-galactosamine (GalN)-induced liver injury. GalN, a well-known hepatotoxicant, causes severe he...

متن کامل

مطالعه اثر عصاره Panax ginseng بر تغییرات هیستومورفومتریک مخ و مخچه در نوزادان 14 روزه موش صحرایی مادران دیابتی

Introduction: Gestational diabetes induces developmental disorders in different parts of CNS and can change dimensions of the cerebrum, cerebellum and spinal cord. Different species of ginseng have been used for many years to control diabetes. This study investigated effect of extract of Panax ginseng on histomorphometric changes on cerebrum and cerebellum in 14 days offsprings rat from diabet...

متن کامل

Ginseng for Liver Injury: Friend or Foe?

Panax sp., including Panax ginseng Meyer, Panax quiquifolius L., or Panax notoginseng (Burk.) FH Chen, have been used as functional foods or for traditional Chinese medicine for diabetes, inflammation, stress, aging, hepatic injury, and cancer. In recent decades, a number of both in vitro and in vivo experiments as well as human studies have been conducted to investigate the efficacy and safety...

متن کامل

Effectiveness of Panax ginseng on Acute Myocardial Ischemia Reperfusion Injury Was Abolished by Flutamide via Endogenous Testosterone-Mediated Akt Pathway

Mechanisms for Panax ginseng's cardioprotective effect against ischemia reperfusion injury involve the estrogen-mediated pathway, but little is known about the role of androgen. A standardized Panax ginseng extract (RSE) was orally given with or without flutamide in a left anterior descending coronary artery ligation rat model. Infarct size, CK and LDH activities were measured. Time-related cha...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 53  شماره 

صفحات  -

تاریخ انتشار 2017